The United States military has confirmed the destruction of the headquarters of Iran’s Islamic Revolutionary Guard Corps (IRGC) in a large-scale strike, escalating tensions across the Middle East.US Central Command (CENTCOM) said the IRGC was responsible for the deaths of more than 1,000 Americans over the past 47 years and described the operation as cutting off “the head of the snake”. According to the statement, the strike has left the IRGC without a central headquarters.Israel also reported carrying out extensive attacks on dozens of Iranian military command centers, including intelligence facilities, IRGC Air Force bases, and internal security sites. Israeli officials said the strikes severely damaged Iran’s command-and-control capabilities and eliminated key personnel.The operations followed the reported killing of Iran’s Supreme Leader on Saturday. Explosions were heard in Tehran overnight as Iran retaliated with missiles and drones targeting Israel, US bases in the Gulf, and regional cities, intensifying fears of broader conflict.The Iranian Islamic Revolutionary Guard Corps (IRGC) killed more than 1,000 Americans over the past 47 years. Yesterday, a large-scale U.S. strike cut off the head of the snake. America has the most powerful military on earth, and the IRGC no longer has a headquarters. pic.twitter.com/WdpN7JBECr— U.S. Central Command (@CENTCOM) March 1, 2026