LONDON — Russell Brand behaved as a “ruthless” sexual predator when he assaulted six women over the course of a decade, a prosecutor said Wednesday as she opened the rape and sexual assault case against the actor-comedian.Brand, 51, has pleaded not guilty to three counts of rape, three counts of sexual assault and one count of indecent assault. The charges involve six women and alleged offenses between 1999 and 2009.Prosecutor Riel Karmy-Jones told jurors at Southwark Crown Court in London that the six women, who do not know each other, were assaulted in “a hotel room, workplaces, a toilet cubicle in a bar and at (Brand’s) home address.”00:31Russell Brand arrives at court for sexual assault trial00:0000:00She said that at the time Brand had an “indiscriminate and voracious” desire for sexual contact, and “women were simply a means to an end.”“He was ruthless, he was calculating, he was manipulative. And, the prosecution say, he was a sexual predator,” Karmy-Jones said.Brand is on bail and arrived at court Wednesday to a crowd of photographers and video journalists. He said he felt “blessed.”“I feel, of course, concerned but hopeful that this process will lead to good outcomes for everybody involved,” Brand said. “That’s my prayer.”Known for risque stand-up routines and battles with drugs and alcohol, Brand rose to prominence in the early 2000s, hosting television programs and his own BBC radio show. He appeared in Hollywood films including “Forgetting Sarah Marshall” and “Get Him to the Greek.”In recent years he has moved away from mainstream media, relocated to Florida and built a large online following with videos mixing wellness, conspiracy theories and discussions of his religious devotion.The Associated Press doesn’t name victims of alleged sexual violence, and British law protects their identities from the media for life.